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Description

Despite PD-L1 expression in tumor cells ranging from 61% to 88%, clinical trials such as CheckMate-143 have failed to show significant survival benefits

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It has also been reported that microglia abnormally fuse to form multinucleated giant cells in spinal cord and brain and in later disease stages microglia showed cytoplasmic fragmentation, indicative of cellular dysfunction and degeneration [119]

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Drug Metabolism Reviews , 47 (3), pp

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doi: 10.1210/mend.10.4.8721983

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